Solicitations - CAPCaT

2019 Award Competition: Center for Advancing Point of Care Technologies in Heart, LungBlood and Sleep Disorders - Pilot Funding Opportunity

LOWELL AND WORCESTER, MA - The University of Massachusetts’ Center for Advancing Point of Care Technologies (CAPCaT) in Heart, Lung, Blood, and Sleep Diseases announces an award solicitation focused on developing, adapting, or validating technologies that can be rapidly applied to heart, lung, blood, or sleep disorders, with additional interest in projects that incorporate complementary and integrative health approaches.

The goal of this communication is to solicit research applications focused on developing, adapting, or validating technologies that can be rapidly applied to heart, lung, blood, or sleep disorders, with additional interest in projects that incorporate complementary and integrative health approaches.

Background Areas of Focus & Performance Criteria Unique Review Criteria FAQs

Use of Funds

CAPCaT Pilot Grant Funding can be used for any of the following purposes:

  • Prototype refinement or optimization
  • Clinical study startup costs
  • Equipment costs, especially if used to validate against a “gold-standard”
  • Manufacturing costs
  • Investigator time
  • Research staff time 
  • Travel to present findings at national meetings
  • Travel to present to the CAPCaT Steering Committee for discussion of milestone achievement

The Center does not support early stage development of prototypes. CAPCaT instead focuses on support of projects that involve refinement of prototypes that require clinical validation and/or user feedback. Functional prototypes that have been validated, when applicable, will be considered as candidates for CAPCaT funding. We are interested in technologies that have the Maturity Level in the Healthcare Innovation Cycle between Proof of Value & Validation of Solution (TRL 4-7).

The CAPCaT training core provides support for statistical analyses and clinician feedback on all funded proposals. The CAPCaT engineering core provides technical and engineering support, when appropriate, on funded proposals. The CAPCaT administrative core provides regulatory and business development support for all funded proposals.

Application Instructions

Point-of-Care Technology award applications are solicited and evaluated in two stages. Applicants must submit pre-proposals, which will undergo review by CAPCaT and NIH scientific staff. A subset of the applicants who submitted pre-proposals will be invited to submit full proposals.  Further details are provided below.

  • The Principal Investigator can be faculty (MD or PhD) from a U.S. college or university or an officer of a small business (MD or PhD not required for small business officer/representative acting as PI).
  • Research applications from inside and outside the UMass system, including international applications, are welcome. While foreign applications are allowed, strong justifications will be needed on why the projects cannot be performed by institutions or business in the United States.
  • Special consideration will be given to early career investigators who may not yet be independent in their pursuits, as mentored experiences are welcomed.
  • Awards under this solicitation may be made only to NIH-eligible applicants. Details regarding specific requirements can be found in the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards.
  • Pre-proposals must be submitted through the POCTRN online system and are due no later than 11:59pm CST on Friday, March 1, 2019. 
  • Awards will be up to $100,000 paid over 12 months.  The funding and length of award will be determined based upon the statement of work and the time and money required to accomplish the milestones. There will be 4-6 awards per year as funds allow.
  • Funding schedules will be tailored based on the needs of the Awardee as described in the budget justification. Awardees will be asked to provide a 6-month project update to the CAPCaT Steering Committee (including science officers from the NHLBI and NICCIH) and continued funding will require demonstration of achieving mutually agreed upon milestones. It is assumed that successful projects will attract additional funding from extramural sources. Awardees will be allowed to solicit further funding through a competitive renewal mechanism.
  • Only direct costs are allowed. Institutional or departmental matching of research funding is not required but would be considered favorably. As such, applicants should consider submitting a letter of support from the appropriate Department or Institutional representative outlining support for the pilot grant application and whether or not there will be matching of CAPCaT funding.
  • Applicants will be notified by Friday, March 15, 2019 as to whether they are invited to submit a full proposal.
  • Invitations will be sent by email both to the PI and to the administrative contact listed in the pre-proposal. Invited full proposals must be received by 11:59pm CST Wednesday, May 15th, 2019
  • Proposals must be submitted through the web-based proposal submission system.
  • Instructions for navigating and completing the full-proposal submission system will be sent with the notification to individuals from whom full-proposals are requested. 

Each full proposal will be peer-reviewed on a confidential basis. All applicants will be informed of review decisions by July 15, 2019. 

If awarded, participation in up to two CAPCaT-related meetings on the UMass Worcester and/or Lowell campuses will be required. Awardees will be expected to provide quarterly updates to the relevant core leads through the POCTRN software platforms, called CoLab and GAITS, and will be required to participate in training activities offered by the Center, including one 2-day program, plus attendance at an annual retreat. Applicants should include these training activities in their proposed budget.

About CAPCaT:
The University of Massachusetts' Center for Advancing Point of Care Technologies (CAPCaT) in Heart, Lung, Blood, and Sleep Diseases (U54HL143541) was recently established with support from the National Heart, Lung, and Blood Institute (NHLBI) as well as the National Center for Complementary and Integrative Health (NCCIH). CAPCaT will make new resources available to pilot awardees and other interested point of care technology researchers. These include access to the National Institutes of Health’s Point of Care Technology Research Network (POCTRN), as well as access to rich technology and business development resources through the Massachusetts Medical Device Development (M2D2) team, clinical translation and validation expertise, as well as a technology training and dissemination unit.

Date: 1/15/2019
CAPCaT Contact:
Mary A. Dubuque, Project Coordinator

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