Solicitations - JHU
Improvements to Rapid Simple Point-of-Care Tests (POCT) For Sexually Transmitted Diseases (STDs)
2020 Tactical Funding Solicitation
The Johns Hopkins University Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases (the Center) is seeking to facilitate the development of novel detection technologies for Point of Care Tests (POCT). The targets for these POCT are limited to sexually transmitted diseases (STDs). Other infectious diseases will not be considered for this award.
Successful applicants will describe improvements to proposed devices which minimally meet or exceed the current clinically accepted assays (i.e., “gold standard”). The proposed device should have achieved a level of technological maturity equivalent to proof of concept at a minimum. The three technological criteria associated with this domain are development of a prototype(s), supportive experimental results, and institutional IP disclosure.
Successful applicants will describe the developmental goals of their device with relevance to a “use case”. A “use case” is defined by the population of patients who would benefit from the device and the end user needs for which development is intended. For example, a “use case” could be a public health clinic with limited funds available for reimbursement of a test. The end user needs and support for reimbursement cost could vary based on whether the clinic is inside or outside the US.
Successful applications will describe the development of tests which minimally meet the ASSURED criteria.
Description of POCT requirements based on ASSURED criteria1
|ASSURED criteria1||Assay Criteria||Criteria Description|
|User-friendly||Low labor burden/CLIA waivable||
|Robust and rapid||Turn-around time (TAT)||
|Equipment-free||Low power reader +no/little sample prep||
|Deliverable to those in need||Portable device||
a United States dollars
Proposed POCT can detect single STDs or multiple STD targets, however, multiplex assays which can detect symptomatically related STDs such as Chlamydia trachomatis (Ct), Neisseria gonorrhoeae (Ng), Trichomonas vaginalis (Tv), and Mycoplasma genitalium (Mg), are preferred. This solicitation is not limited to the four targets named. Proposals are encouraged which detect STDs other than those listed above, particularly syphilis.
Proposals should limit the work to tasks that can be completed within 6 months.
Key Dates for Application and Anticipated Award Deadlines
|Solicitation Release||January 22, 2020|
|Expression of Interests Due||March 2, 2020, 5 pm EST|
|Invitations for Full Fast Track Proposals||April 1, 2020|
|Full Fast Track Proposals Due||June 1, 2020, 5 pm EDT|
|Notification of Successful Applicants||July 22, 20202|
|Review Notification to all Applicants||July 29,2020|
|Funds Awarded (anticipated)||Approximately 60 days following notifications of successful application|
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